Papers

2009年份出版刊物 - 最新优先


  • High-throughput screening reveals a small-molecule inhibitor of the renal outer medullary potassium channel and Kir7.1

    Lewis L.M., Bhave G., Chauder B.A., Banerjee S., Lornsen K.A., Redha R., Fallen K., Lindsley C.W., Weaver C.D.,

    Denton J. Mol. Pharmacol., 2009, 76(5), 1094-1103.

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  • Robotic multiwell planar patch-clamp for native and primary mammalian cells

    Milligan C.J., Li J., Sukumar P., Majeed Y., Dallas M.L., English A., Emery P., Porter K.E., Smith A.M., McFadzean I.,

    Beccano-Kelly D., Bahnasi Y., Cheong A., Naylor J., Zeng F., Liu X., Gamper N., Jiang L., Pearson H.A., Peers C., Robertson B., Beech D.J.

    Nature Protocols, 2009, 4(2), 244-255. 


    Screenshots from this publication:

    Images of HEK 293 cellsplanar whole-cell patch-clamp data, HEK 293 cellsPlanar whole-cell patch-clamp data from native and primary cells


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  • Port-a-Patch and Patchliner: High fidelity electrophysiology for secondary screening and safety pharmacology

    Farre C., Haythornthwaite A., Haarmann C., Stoelzle S., Kreir M., George M., Brüggemann A., Fertig N.

    Comb. Chem. & HTS, 2009, 12 (1), 24-37.

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  • Ion channel screening – automated patch clamp on the rise

    Farre C., George M., Brüggemann A., Fertig N.

    Drug Discovery Technology, 2009.

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  • Amyloid-beta-Induced Ion Flux in Artificial Lipid Bilayers and Neuronal Cells: Resolving a Controversy

    Capone R., Quiroz F.G., Prangkio P., Saluja I., Sauer A.M., Bautista M.R., Turner R.S., Yang J., Mayer M.

    Neurotox. Res., 2009, 16(1), 1-13. Epub 2009 Mar 19.

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  • The M34A mutant of Connexin26 reveals active conductance states in pore-suspending membranes

    Gaßmann O., Kreir M., Ambrosi C., Pranskevich J., Oshima A, Röling C., Sosinsky G., Fertig N., Steinem C.

    Journal of Structural Biology, 2009, 168 (1), 168-176.

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  • High throughput techniques for discovering new glycine receptor modulators and their binding sites

    Gilbert D.F.,Islam R., Lynagh T., Lynch J.W., Webb T.I. Front.

    Mol. Neurosci., 2009, 2(17), 1-10. Epub 2009 Oct 30

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  • Transient receptor potential ankyrin 1 antagonists block the noxious effects of toxic industrial isocyanates and tear gases

    Bessac B.F., Sivula M., von Hehn C.A., Caceres A.I., Escalera, J, Jordt S.

    FASEB Journal, 2009; 23, 1102-1114.

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