Papers

2011年份出版刊物 - 最新优先


  • Chimeric approach reveals that differences in the TRPV1 pore domain determine species-specific sensitivity to block of heat activation
    Papakosta M., Dalle C., Haythornthwaite A., Cao L., Stevens E.B., Burgess G., Russell R., Cox P.J., Phillips S.C., Grimm C.

    J. Biol. Chem., 2011 Sep 12. [Epub ahead of print]

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  • Thermosensitive transient receptor potential channels in human corneal epithelial cells

    Mergler S., Garreis F., Sahlmüller M., Reinach P.S., Paulsen F., and Pleyer U.

    J. Cell. Physiol., 2011, 226, 1828 - 1842 

    2011_Mergler_JPhys_small

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  • Rapid and Contrasting Effects of Rosiglitazone on Transient Receptor Potential TRPM3 and TRPC5 Channels
    Majeed Y, Bahnasi Y, Seymour VAL, Wilson LA, Milligan CJ, Agarwal AK, Sukumar P, Naylor J, and
    Beech DJ 

    Mol. Pharmacol., 79(6),1023-30, 2011

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  • Nanopore-based single-molecule mass spectrometry on a lipid membrane microarray

    Baaken G., Ankri N., Schuler A.K., Rühe J., Behrends C.

    Am. Chem. Soc Nano, 5(10), 8080-8088, 2011

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  • Green fluorescent protein changes the conductance of connexon 43 hemichannels reconstituted in planar lipid bilayers
    Christian Carnarius , Mohamed Kreir, Marcel Krick, Christoph Methfessel, Volker Moehrle, Oliver Valerius, Andrea Brüggemann, Claudia Steinem, Niels Fertig

    Journal of Biological Chemistry, Published on December 3, 2011 as Manuscript M111.319871

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  • State-of-the-art automated patchclamp devices: heatactivation, actionpotentials, and highthroughput in ionchannel screening

    Sonja Stoelzle, Alison Obergrussberger, Andrea Brüggemann, Claudia Haarmann, Michael George, Ralf Kettenhofen and Niels Fertig

    Frontiers in Pharmacology, November 2011, Volume 2 , Article 76

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  • Automated electrophysiology makes the pace for cardiac ion channel safety screening

    Clemens Möller, Harry Witchel

    Frontiers in Pharmacology, November 2011, Volume 2, Article 73

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  • Thermo-sensitive transient receptor potential vanilloid channel-1 regulates intracellular calcium and triggers chromogranin A secretion in pancreatic neuroendocrine BON-1 tumor cells
    Stefan Mergler, Marek Skrzypski, Maciej Sassek, Piotr Pietrzak, Christina Pucci, Bertram Wiedenmann, Mathias Z. Strowski

    Cellular Signalling 24 (2012) 233–246

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  • Characterization of transient receptor potential vanilloid channel 4 (TRPV4) in human corneal endothelial cells

    Stefan Mergler,, Monika Valtink, Katrin Taetz, Monika Sahlmüller, Gabriele Fels, Peter S. Reinach, Katrin Engelmann and Uwe Pleyer

    Experimental Eye Research 93 (2011) 710e719

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  • Development of a selective small-molecule inhibitor of Kir1.1, the Renal Outer Medullary Potassium Channel
    Gautam Bhave1, Brian A. Chauder1, Wen Liu2, Eric S. Dawson1, Rishin Kadakia1, Thuy T. Nguyen1, L. Michelle Lewis1, Jens Meiler1, C. David Weaver1, Lisa M. Satlin2, Craig W. Lindsley1 and Jerod S. Denton1, 

    Molecular Pharmacology, 2011, 79(1), 42-50

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  • Automated Patch Clamp on mESC-Derived Cardiomyocytes for Cardiotoxicity Prediction

    Stoelzle S, Haythornthwaite A, Kettenhofen R, Kolossov E, Bohlen H, George M, Brüggemann A, Fertig N.

    J Biomol Screen. 2011 Jul 20. [Epub ahead of print]
    Image from the paper:

    2011_Stoelzle_small

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  • Physiologie des humanen Hornhautendothels - neue Erkenntnisse durch elektrophysiologische Untersuchungen

    Mergler S. and Pleyer U.

    Klin. Monatsbl. Augenheilkd., 2011, 228, 520 - 524 

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  • Voltage-gated sodium channel (NaV) protein dissection creates a set of functional pore-only proteins

    David Shaya, Mohamed Kreir, Rebecca A. Robbins, Stephanie Wong, Justus Hammon, Andrea Brüggemann, and Daniel L. Minor, Jr

    PNAS Early Edition, 2011, 1 - 6
    Screenshot from the paper:

    PNAS_2011_single_channels_small

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  • Pharmacological studies of Cav3.1 T-type calcium channels using automated patch-clamp techniques

    Kee-Hyun Choi, Chiman Song, Chan S. Cheong and Hyewhon Rhim

    Gen. Physiol. Biophys., 2011, 30100–105

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  • Chemical and biological characterization of four new linear cationic a-helical peptides from the venoms of two solitary eumenine wasps
    Marisa Rangel, Marcia Perez dos Santos Cabrera, Kohei Kazuma, Kenji Ando, Xiaoyu Wang, Manabu Kato, Ken-ichi Nihei, Izaura Yoshico Hirata, Tyra J. Cross, Angélica Nunes Garcia, Eliana L. Faquim-Mauro, Marcia Regina Franzolin, Hiroyuki Fuchino, Kanami Mori-Yasumoto, Setsuko Sekita, Makoto Kadowaki, Motoyoshi Satake, Katsuhiro Konno

    Toxicon,2011, 57,1081–1092

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  • Book chapter: 'Cardiac Toxicity'

    Ralf Kettenhofen and Silke Schwengberg 

    ADMET for Medicinal Chemists: A Practical Guide, Edited by Katya Tsaioun and Steven A. Kates, John Wiley & Sons, 

    Inc., 2011, 287 - 314

  • Functional analysis of synthetic substructures of polytheonamide B: A transmembrane channel-forming peptide
    Matsuoka S, Shinohara N, Takahashi T, Iida M, and Inoue M 

    Angew. Chem. Int. Ed., 50, 4879 – 4883, 2011

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