2012年份出版刊物 - 最新优先

  • Characterizing Human Ion Channels in Induced Pluripotent Stem Cell-Derived Neurons
    Haythornthwaite A, Stoelzle S, Hasler A, Kiss A, Mosbacher J, George M, Brüggemann A, Fertig N.

    J Biomol Screen. 2012 Oct;17(9):1264-72. Epub 2012 Aug 24.


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  • Effects of the Antitussive Drug Cloperastine on Ventricular Repolarization in Halothane-Anesthetized Guinea Pigs

    Takahara A, Fujiwara K, Ohtsuki A, Oka T, Namekata I, Tanaka H.

    J Pharmacol Sci. 2012 Nov 16;120(3):165-75.


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  • Toward a new gold standard for early safety: automated temperature-controlled hERG test on the Patchliner

    Polonchuk L

    Frontiers in Pharmacology, 2012, Vol 3, Article 3, 1-7

    Polonchuk137x100 Polunchuk_Table2_167x100

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  • Design, synthesis and functional analysis of dansylated polytheonamide mimic: an artificial Peptide ion channel

    Itoh H., Matsuoka S., Kreir M., Inoue M.

    J. Am. Chem. Soc. 134, 14011, 2012

  • Insulin-secreting INS-1E cells express functional TRPV1 channels

    Fågelskiöld A.J., Kannisto K., Boström A., Hadrovic B., Farre C., Eweida M., Wester K.and Islam MD.S.

    Islets. 4:1, 1–8, January/February 2012

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  • Regulation of Hyperpolarization-activated Cyclic Nucleotide-gated (HCN) Channel Activity by cCMP

    Zong X, Krause S, Chen CC, Krüger J, Gruner C, Cao-Ehlker X, Fenske S, Wahl-Schott C, Biel M.

    J Biol Chem., 2012 Aug, 3;287(32):26506-12.

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  • TRPA1 Agonist Activity of Probenecid Desensitizes Channel Responses: Consequences for Screening

    McClenaghan C, Zeng F, Verkuyl JM

    Assay Drug Dev Technol., 2012 Jun 8

  • DNA unzipping and protein unfolding using nanopores

    Merstorf C, Cressiot B, Pastoriza-Gallego M, Oukhaled AG, Bacri L, Gierak J, Pelta J, Auvray L, Mathé J.

    Methods Mol Biol. 2012;870:55-75.

  • Isolation, characterization and total regioselective synthesis of the novel μO-conotoxin MfVIA from Conus magnificus that targets voltage-gated sodium channels

    Vetter I, Dekan Z, Knapp O, Adams DJ, Alewood PF, Lewis RJ.

    Biochem Pharmacol. 2012 Aug 15;84(4):540-8

  • Interleukin-1R3 mediates interleukin-1–induced potassium current increase through fast activation of Akt kinase

    Qian J, Zhu L, Li Q, Belevych N, Chen Q, Zhao F, Herness S, Quan N.

    Proc Natl Acad Sci U S A. 2012 Jul 24;109(30):12189-94

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  • Hydrophobic gating of mechanosensitive channel of large conductance evidenced by single-subunit resolution

    Birkner JP, Poolman B, Koçer A.

    Proc Natl Acad Sci USA. 2012 Aug 7;109(32):12944-9

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  • Synthesis and in vitro antibacterial activity of novel 3-azabicyclo[3.3.0]octanyl oxazolidinones

    Bhattarai D, Lee SH, Seo SH, Nam G, Kang SB, Pae AN, Kim EE, Oh T, Cho SN, Keum G.

    Chem Biol Drug Des. 2012 Sep;80(3):388-97

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  • Observation of Antinociceptive Effects of Oxymatrine and its Effect on Delayed Rectifier K+ Currents (Ik) in PC12 Cells

    Wang Y, Yuan J, Yuan X, Wang W, Pei X, Zhao Q, Cao H, Xu M, Liu Z.

    Neurochem Res., 2012, Jul 20

  • Natural and artificial ion channels for biosensing platforms

    Steller L., Kreir M., Salzer R.

    Anal Bioanal Chem. (2012) 402:209–230

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  • Selective modification of the N-Terminal structure of polytheonamide B significantly changes its cytotoxicity and activity as an ion channel
    Shinohara N, Itoh H, Matsuoka S, and Inoue M

    ChemMedChem, published online April 4th, 2012

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  • Calcium regulation by thermo- and osmosensing transient receptor potential vanilloid channels (TRPVs) in human conjunctival epithelial cells

    Stefan Mergler, Fabian Garreis, Monika Sahlmüller, Ekaterini-Maria Lyras,

    Peter S. Reinach, Abhilash Dwarakanath, Friedrich Paulsen, Uwe Pleyer

    Histochem. Cell. Biol., Published online February 12 2012

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  • HTS techniques for patch clamp-based ion channel screening - advances and economy

    Farre C and Fertig N

    Expert Opin. Drug Disc. early online publication April 2012

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